Exploring the Chemistry of Retinoids and Skin Health

#099 Rebroadcast

In this special re-release episode, Melissa and Jam dive deep into the world of Vitamin A (retinol) and its role in anti-aging skincare. They revisit a popular episode that explores whether anti-aging products genuinely work. The hosts break down the scientific functions of the skin, the impact of UV radiation, and the importance of sunscreen. They also discuss how retinoids (vitamin A) can help repair and maintain the skin's structure, backed by peer-reviewed studies. This episode is a blend of chemistry, practical skincare tips, and personal anecdotes.

00:00 Introduction to Vitamin A and Anti-Aging
00:10 Revisiting the Anti-Aging Episode
00:36 Personal Reflections on Skincare
02:06 Acknowledging Influences and Inspirations
04:57 Understanding Skin and Aging
07:55 The Role of Fibroblasts and Proteins
10:55 Impact of UV Rays on Skin Aging
14:10 Importance of Sunscreen
15:56 Retinoids: The Gold Standard in Anti-Aging
19:50 Retinoid Study Results
20:31 Retinoids: The Antidote to Sun Damage
21:34 The Importance of Sunscreen
23:45 Understanding Skin Structure
26:08 How Retinoids Work
29:44 Fun Facts and Warnings About Retinoids
34:02 Personal Stories and Reflections
38:33 Conclusion and Listener Engagement

References from this episode

1. https://www.jidonline.org/action/showPdf?pii=S0022-202X%2815%2940798-5
2. https://www.jidonline.org/article/S0022-202X(15)40798-5/fulltext
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791161/#:~:text=Retinoids%20are%20also%20commonly%20known,and%20promotes%20angiogenesis%20%5B13%5D
4. https://www.acs.org/content/acs/en/molecule-of-the-week/archive/v/vitamin-a.html
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699641/
6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791161/#:~:text=Firstly%2C%20retinol%20is%20converted%20to,to%20the%20retinoic%20acid%20receptors.&text=Retinol%20concentration%20in%20the%20cosmetic,the%20oxidized%20form%20of%20retinol
7. https://youtu.be/grxmyM7EuDk
8. https://pubs.acs.org/doi/10.1021/acsomega.0c02102
9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790843/
10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583892/#R60
11. https://cen.acs.org/articles/95/i10/Periodic-graphics-anti-aging-creams.html
12. https://www.acs.org/content/acs/en/pressroom/reactions/videos/2017/are-anti-aging-creams-legit.html

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