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Prognostic significance of splicing factor gene mutations in AML; therapy resistance in multiple myeloma; the effects of KIT ligand deletion on HSC homeostasis

Blood Podcast

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Prognostic significance of splicing factor gene mutations in AML; therapy resistance in multiple myeloma; the effects of KIT ligand deletion on HSC homeostasis

This chapter discusses the prognostic significance of splicing factor gene mutations in AML and the therapy resistance mechanisms in multiple myeloma, emphasizing the importance of considering treatment context and characterizing resistance mechanisms at the subclone level.

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