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Episode 18 - Pretty Not Happy (with blood) | Paroxysmal Nocturnal Haemoglobinuria

Bloody Minded

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Diagnosing Paroxysmal Nocturnal Haemoglobinuria Through Flow Cytometry

This chapter delves into the diagnostic process for Paroxysmal Nocturnal Haemoglobinuria using flow cytometry, focusing on the measurement of GPI-associated protein expressions in diverse blood cell types. It highlights the complexities of accurately diagnosing PNH, including the impacts of red cell lifespans and blood transfusions on clonal size assessment.

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