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Freely Filtered 028: Finerenone for diabetic kidney disease
Freely Filtered, a NephJC Podcast
Is This Bayer's First Foray Into the Kidney World?
14,000 patients total underwent screening and finally randomized 5,734 patients of which 60 of them were prospectively excluded. The baseline characteristics were really pretty well balanced between the two groups. Patients were followed for a median of 2.6 years and overall there was really good adherence to the trial regimen at just over 92%. And so now if we get to the really exciting part that we're all here for, figure one, we see the primary composite outcome of kidney failure,. A sustained decrease of at least 40% in EGFR from baseline or death from renal causes occurred significantly less than those that received the narrow known at 17.8% compared to 21.1% in the placebo arm
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