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59 - Hyperkalemic Heparin

The Curious Clinicians

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Is Heparin a Good Diuretic?

In the early 1960s, there weren't a lot of great diuretic options available. Furosemide was still in development and I think that came out in the mid 1960s. A case series from 1960 reported the results of using heparin deliberately as a diuretic in 29 hypervolemic patients. And amazingly, almost all of the patients in this study achieved diuresis while on heparin.

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