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Genetics, Constantly Evolving

ACR Journals On Air

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The Role of Urate Transporters in Gout

I saw that you generated actually two risk scores, one for Gout and one for serum urate. And I am a simple clinician. So my instinct was that those should overlap. Could you explain the rationale for looking at both and did they overlap? Okay, they do substantially overlap. There were one or two loci that in our Gout GWAS that we didn't see in the U-H-E-WAS, which suggests that they are involved in the inflammatory process of Gout. Interesting. Yeah,. no, that makes sense.

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