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Freely Filtered 060: HCTZ v Kidney Stones, The NOSTONE trial
Freely Filtered, a NephJC Podcast
The Benefits of a Composite Outcome
The composite outcome is also useful because you get more number of events. My concern was that it was capturing stones that had been present before the trial started. It wasn't clear enough to me that it was a just looking at what defined stone growth and then my worry was that some of these stone passage events were actually indicating stones that had already been present at the start of the trial passing. And so that's or two separate things.
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