
Dr. Dietrich Stephan: New Drugs that Repair Broken Genes
Talking Biotech with Dr. Kevin Folta
00:00
Drug Development
Every human disease is genetic, yet almost all drugs that are on the market target downstream proteins. And so you have to scratch your head and say, well, wait, if root causality is at the genum level, why are we drugging proteins, which are the final step in the central dogma? The answer there is because the genom has evolved in a double helical structure that we're all familiar with from high school biology, to protect itself. This is existential information. It's the print of life. Drugs have difficulty getting in there and engaging with a mutin gen,. That's the technolge that’s the problem that we decided to solve. Open up
Transcript
Play full episode