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The Pros and Cons of Editing a Gene
There are four PPO genes in avocado and we only think there's one that's important to confer the non browning phenotype. And so but they're all similar because they're all of the same gene family. The science is fairly clear now and shows this is worked on in corn and in tomato and rice That this level of off target CRISPR edits is is at or below the mutation the the random mutation rate you might see in conventional breeding.