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Gene Expression in Neurons Solves a Brain Evolution Puzzle

The Quanta Podcast

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Toscaz's Lab Performed Single-Cell RNA Sequencing on Salamander Brain Cells

Toscaz's lab performed single-cell RNA sequencing on thousands of salamander brain cells and compared the results to data collected previously from reptiles and mammals. Many salamander brains, each about one-fiftyth the volume of a mouse brain, were painstakingly prepared and labeled by the researchers. The brains were then put into a machine about the size of a shoebox that prepared all the samples for sequencing in about 20 minutes.

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