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Genetics
Most cells in our bodies never ever stop that feedback process. If you have an injury in your skin, it goes all the way back to changing what will be transcribed by cells in your heart and brain. We're continuously studying when and how what kind of gens get expressed. Even with this only laughable on giga bite of base pears in the gino, that's not much information. Without having prior outcome information, there's no other way to program this.