What Is the Shaker Peptide?

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Toto applied to the US government for funding twice. Got denied twice. And on an appeal, he got it. From the National Institute of General Medical Sciences. The shaker peptide is clearly potent. Incredibly potent. Very, very small amounts would cause mice to shake. Like as if they were having a seizure or something? It was like a tremor, uncontrollable tremor. But only bound to the region where pain fibers come in.

After years of being publicly shamed for “fleecing” the taxpayers with their frivolous and obscure studies, scientists decided to hit back with… an awards show?! This episode, we gate-crash the Grammys of government-funded research, A.K.A. the Golden Goose Awards. The twist of these awards is that they go to scientific research that at first sounds trivial or laughable but then turns out to change the world. We tell the story of one of the latest winners: a lonely Filipino boy who picked up an ice cream cone that was actually a covert vampire assassin. Decades later, that discovery leads to an even bigger one: an entire pharmacy's worth of new drugs hidden just below the surface of the ocean.

EPISODE CREDITS:

Reported by - Latif Nasser and Maria Paz Gutiérrezwith help from - Ekedi Fausther-KeeysProduced by - Maria Paz Gutiérrez and Matt Kieltywith help from Ekedi Fausther-KeeysOriginal music and sound design contributed by Matt Kieltywith mixing help from Arianne Wack. Fact-checking by Emily KriegerEditing by Soren Wheeler, who thought the whole episode should have been a little shorter.

Special thanks to Erin Heath, Haylie Swenson, Gwendolyn Bogard, Valeria Sabate and everyone else at AAAS who oversee the Golden Goose Awards. Also to Maggie Luddy, and former Congressman Jim Cooper, Terry Lee Merritt at University of Utah, Jim Tranquada, John McCormack, and the Cosman Shell Collection at Occidental College.

CITATIONS:

Videos -

Gorgeous slo mo video of cone snails hunting (https://zpr.io/uiWrS3J2BuZM).

A recent segment from our down-the-hall neighbors at On The Media (https://zpr.io/VZHSLPdkdAxH) about breakthrough science featuring the late Senator William Proxmire.

Check out dazzling documentary shorts on each of the Golden Goose Awards winners (https://zpr.io/Tpxxrzzuz6GS) on their website.

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