If your T4 is being preferentially shunted into reverse T3, instead of T3, you might feel like you have the symptoms of hyperthyroidism. The standard treatment for hypothyroidism is to give T4 - a synthetic version of this hormone. Most patients will convert that T4 via D1 and D2 into T3. It will go on to have all the biologic effects and it will also suppress TRH and TSH  and the body will come back into line.

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