In an ancestral environment, having too much fat on your body is not really something that happens very often. If you look at hunter gatherers, obesity is like, as far as I can tell, basically non-existent. There is no evolutionary incentive to evolve a strong protective mechanism against fat gain. And so it really looks like we, at least most people, there's an asymmetry where the system works really well at defending against fat loss, not as well against fat gaining.

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