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TWiV 1191: The pandemic duo

This Week in Virology

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Bats: Evolution and Immunity

This chapter explores the genomic adaptations of bats that enable them to tolerate viruses and resist diseases, focusing on the ISG15 gene's role in combating SARS-CoV. The speakers discuss the unique evolutionary traits of bats, their enriched immune system genes, and the implications of bat genome sequencing through the Bat 1K Project. They also address the critical need for collaborative research in understanding the relationship between bats and the viruses they carry, while examining the broader ecological impacts and animal behaviors.

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