Unpacking the Mechanics of Large Language Models

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Episode 68: How is Google DeepMind pushing the boundaries of AI to tackle drug discovery, robotics, and even autonomous AI agents? Matt Wolfe (https://x.com/mreflow) sits down with DeepMind CEO Sir Demis Hassabis (https://x.com/demishassabis), a neuroscientist, AI pioneer, Nobel laureate, and knight, to peel back the curtain on Google’s latest advances—and the ethical challenges that come with them.

In this episode, Matt and Demis go deep on what’s powering the newest generation of AI agents, how models like AlphaFold and AlphaEvolve are accelerating scientific breakthroughs, and why world models are so important for the future of robotics. Demis shares why he believes AI is poised to reshape society—for better and for worse—and what Google is doing to build public trust in its systems.

Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd

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Show Notes:

• (00:00) AI Revolutionizing Drug Discovery

• (03:35) Advanced Model Training Methods

• (07:06) Accelerating Drug Discovery with AI

• (11:12) AI's Responsible Role in Society

• (13:56) AI Revolutionizing Science & Life

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Mentions:

• Sir Demis Hassabis: https://www.linkedin.com/in/demishassabis/

• Google DeepMind: https://deepmind.google/

• AlphaFold: https://alphafold.ebi.ac.uk/

• AlphaEvolve: https://deepmind.google/discover/blog/alphaevolve-a-gemini-powered-coding-agent-for-designing-advanced-algorithms/

• Isomorphic Labs: https://www.isomorphiclabs.com/

• Android XR glasses: http://blog.google/products/android/android-xr-gemini-glasses-headsets/

Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw

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Check Out Matt’s Stuff:

• Future Tools - https://futuretools.beehiiv.com/

• Blog - https://www.mattwolfe.com/

• YouTube- https://www.youtube.com/@mreflow

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Check Out Nathan's Stuff:

• Newsletter: https://news.lore.com/

• Blog - https://lore.com/

The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano