On March 29, 2023, we released an episode titled, “The 4 PCOS Phenotypes”. That was in 2023! Now, on 29 October 2025, in the journal Nature Medicine, researchers have published, “Data-driven (FOUR) subtypes of polycystic ovary syndrome and their association with clinical outcomes”. PCOS is not ONE condition: is a constellation of metabolic, endocrine, and ovulatory dysregulation. We covered these 4 phenotypes back then. Is this what the “new data” found? Or what it something else? And how does these affect IVF or pregnancy outcomes? Listen in for details!
1. Gao, X., Zhao, S., Du, Y. et al. Data-driven subtypes of polycystic ovary syndrome and their association with clinical outcomes. Nat Med (2025). https://doi.org/10.1038/s41591-025-03984-1
2. Mar 29, 2023; SPOTIFY: https://creators.spotify.com/pod/profile/dr-hector-chapa/episodes/The-4-PCOS-Phenotypes-e217vv0/a-a9ipgjs
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