2min chapter

Immune cover image

Immune 27: Trained immunity

Immune

CHAPTER

NK Cells in CD45.1 Congenital Mice - Is There a Difference?

In 2018, as published, they found that at the NCR1 locus, which is a receptor on NK cells, were different in CD45.1 congenital mice. And even though... So the papers definitely prompted rechecking of all the mice, and they said they saw no differences. I think that's something to consider when specifically looking at NK cells in this mouse, this model. It wasn't always well stated, because they really brought up in the beginning how those first ex vivo and vitro studies were enriched. There could be contaminants.

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