Glutamate is more prominent in a delta by the glutamate binding to the second order neuron. It's going to cause a influx of sodium and other positive ions into the second order neurons, which then causes an action potential to begin on them. And it makes sense goes from the spine. So that a sense up what's called the spino thalamic tract. But there will be some neurons that would jump out at the brainstem level. That gives a small degree activation of the reticular formation.