Episode 041: Myeloma Series, Pt.2 - Intro to MGUS and Smoldering Myeloma
The Fellow on Call: The Heme/Onc Podcast
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The Importance of Monitoring Patients for Multiple Myeloma
The biggest predictor for progression to overt multiple myeloma is an MSBIC that rises by.5 and a decreasing hemoglobin of.5 over the course of a year. Only about half of those will develop multipleMyeloma at 10 years, so even then it's not quite definite. A patient who has a 24-hour U-pep with greater than 500 milligrams of monoclonal protein collected over 24 hours could still be defined as having smolderingMultiple Myeloma.
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