BMT as initial treatment for severe aplastic anemia, macrophage metabolic rewiring in sickle cell disease, and predicting outcomes using PET radiomics in diffuse large B cell lymphoma
Blood Podcast
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Baseline Pet Radiomics Outperform the IPI Risk Score for Prediction of Outcome in Diffuse Large B-Cell Lymphoma
impaired epharocytosis is the key driver of hepatic damage and chronic inflammation in sickle cell disease. Hemolysis plays a major role in this process by reprogramming macrophages towards highly inflammatory cells. Reversing these defects through reactivation of the PPAR-gamma PGC-1-alpha pathway leads to a therapeutic benefit for SCD.
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