Prion Like Misfolding

Parkinson's disease often starts in the gut with a form of proachin. The immune cells take up prion protein and carry it into the spleen. It then travels along the nerve fibres, particularly the vaguest nerve, up to the brain. And when it reaches the brain, the neurons get infected by misfolded proteins. So long before symptoms, you can have lots of these proteins misfolded in your body,. unable to be cleared. In amloid plac this takes a long time, i would imagine, to develop, usually, writimg these ed things at right, happen over ies, right? Yes. Oh, but i ill think am