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The History of the Finius Gauge Story
Neuroscience psychology has a really horrific history of human experiments, both on slaves and on humans that were in asylums. So I wouldn't surprise me if there was historic evidence of it not being perhaps as dramatic of a Dr. Jekyll Mr. Hyde situation as the tale that we tell to undergrads. In the absence of executive function in the prefrontal cortex, that type of temper and unpredictability is absolutely something that we have seen in more just that one case.