Exploring the prevalence of flawed or faked clinical trials and the potential dangers they pose in various medical fields, this chapter discusses the argument for reviewing individual patient data to identify hidden flaws. It also highlights examples of fraudulent trials and the need to remove untrustworthy work from systematic reviews.
Investigations suggest that, in some fields, at least one-quarter of clinical trials might be problematic or even entirely made up. Faked or unreliable trials are dangerous, as they could end up being included in the reviews that help inform clinical treatments. However, the extent of the problem in unclear, and many researchers urge stronger scrutiny.
This is an audio version of our Feature: Medicine is plagued by untrustworthy clinical trials. How many studies are faked or flawed?
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