Exploring Gene Expression and Drug Discovery

The chapter dives into the speaker's journey from gene cloning to understanding gene expression, highlighting their shift towards exploring gene control in mammalian cell systems. It discusses the creation of a commercial institute called Seros with Jay Bradner, focusing on studying enhancers in tumor cells for targeted therapies. The chapter also details the company's focus on developing treatments by targeting genes like nuclear hormone receptors in AML through super enhancers.