The Fellow on Call: The Heme/Onc Podcast cover image

Episode 077: Management of relapsed diffuse large B-cell lymphoma (DLBCL) - part 1

The Fellow on Call: The Heme/Onc Podcast

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Managing Relapsed DLBCL with CNS Involvement

This chapter focuses on the clinical management strategies for a 63-year-old male with relapsed diffuse large B-cell lymphoma (DLBCL) exhibiting central nervous system (CNS) symptoms. It reviews treatment options, the importance of distinguishing types of CNS involvement, and evaluates key therapeutic approaches including chemotherapy and stem cell transplant versus CAR-T therapy.

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