Is Race Better Than Biology?

The Filtrate:

Matt Sparks

Joel Topf

Swapnil Hiremath

Samira Farouk

Jennie Lin

And three special guests:

Carina Seah a second year MD PhD student Mt Sinai who led the initiative to remove race from the eGFR formulas

Poyan Mehr, founder of GlomCon and author of this post on the use of race in eGFR estimating formulas.

Deidra Crews Professor of Medicine and researcher in health disparities.

Show Notes:

Petition for Removal of “Race Correction” in eGFR at Mount Sinai https://docs.google.com/document/d/1vJCwVndyzemWCx8RXZLvLm6JLuFN7NdgEFVCFaDnSOk/edit

Dr Murphy, Dean For Clinical Integration And Population Health. Professor And System Chair. https://icahn.mssm.edu/profiles/barbara-murphy

The Bowman Society at the University of Chicago. I can not find a recording of the webinar https://pritzker.uchicago.edu/resources/bowman-society

Social Determinants of Racial Disparities in CKD https://jasn.asnjournals.org/content/27/9/2576

Socioeconomic Disparities in Chronic Kidney Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291541/

Shortcomings of the current GFR estimating equations https://pubs.glomcon.org/archives/1491

Alan S Go’s work on eGFR, hospitalization and death: https://www.nejm.org/doi/full/10.1056/nejmoa041031

Tangri Kidney Failure Risk Calculation https://kidneyfailurerisk.com

De-adjusting for body surface area: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756662/

2018 Nature Reviews Nephrology Porrini Estimated GFR: time for a critical appraisal https://www.nature.com/articles/s41581-018-0080-9

Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C https://www.nejm.org/doi/full/10.1056/nejmoa1114248

Transdermal Measurement of Glomerular Filtration Rate in Mice https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235579/

Worldwide Frequencies of Apolipoprotein L1 Renal Risk Variants https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482949/

Health Affairs Blog about when and how to measure race in research: https://www.healthaffairs.org/do/10.1377/hblog20200630.939347/full/

ASN Kidney Stars https://www.asn-online.org/grants/travel/details.aspx?app=MSR