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#377 — The Future of Psychedelic Medicine 2

Making Sense with Sam Harris

CHAPTER

MDMA Therapy: Challenges and Controversies

This chapter explores the debates surrounding the use of MDMA as a treatment for PTSD, highlighting concerns raised by an FDA advisory committee regarding the quality of evidence supporting its efficacy. It examines the unique challenges of conducting double-blind studies with psychedelics and the impact of participant perceptions on trial outcomes. The discussion emphasizes the need for advancements in therapeutic models and regulatory frameworks to support the integration of psychedelics in mental health treatments.

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