The main way caffeine works is it blocks a receptor in the brain so there is a compound called adenosine which kind of lets our cells know that we're getting tired. When the caffeine eventually degrades depending on the person maybe around five hours later that's when the crash comes now. There are those people who you know who can have in a double espresso after dinner for me absolutely no caffeine after 3 p.m. It seems like caffeine is maybe not the wonder drug that we thought it was and yet i'm not sure i'm ready to give it up just yet flora. If you go to nature.com slash briefing and sign up for our newsletter i will email stories like this and

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