Genetic issues in dog breeds and the regulatory path for lifespan-extending drugs

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This chapter explores the genetic issues in certain dog breeds caused by inbreeding and the lack of genetic diversity in the past. The importance of the FDA's regulatory path in developing drugs for lifespan extension is discussed, along with a brief mention of stem cell therapy and supplements as potential pathways for lifespan extension.

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Today’s show:

Loyal CEO and Founder Celine Halioua joins Jason to discuss developing drugs that delay dog aging (10:19), lessons learned as a solo founder (49:34), and much more!

Time stamps:

(0:00) Loyal CEO Celine Halioua joins Jason

(1:43) The human dream of achieving life extension

(4:37) Celine’s background

(8:48) Fount - Get $500 off at https://fount.bio/twist

(10:19) Why Celine decided to start with a focus on dogs

(16:43) Wegovy, Ozempic, and the category of drugs that Loyal is developing

(20:44) Breaking down how the drugs work and the consequences of selective breeding

(24:21) LinkedIn Jobs - Post your first job for free at https://linkedin.com/unicorn

(25:36) Stem cell therapy and the placebo effect

(33:29) Environmental factors to consider in drug development

(37:05) The path to commercialization