6min chapter

ACR on Air cover image

47. Autoinflammatory Disease

ACR on Air

CHAPTER

The Role of Immunoglobulin in Familial Mediterranean Fever

Dan Kastner: I came to the NIH and started at least the laboratory side of my rheumatology fellowship working on lupus. The idea was that there was some sort of skewing of the immunoglobulin repertoire, both in patients and in mouse models of lupus as well. And so I developed this fairly elaborate mouse system for testing that hypothesis,. That's how you know, a fast friend years and years later, because I had come up with something that prevented him from having episodes. But then you put that exciting event of making that diagnosis and making a patient better with the fact that two years into my fellowship, all of a sudden, I was at

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