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Improving Outcomes with First-Line Endocrine-Based Therapy for Patients with HR-Positive, HER2-Negative Metastatic Breast Cancer

Breast Cancer Update

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Empowering Patients: Endocrine Resistance Insights in Breast Cancer

This chapter emphasizes the essential role of patient involvement in breast cancer treatment decisions, particularly in hormone receptor-positive cases. It explores clinical data on endocrine resistance, notably the impact of ESR1 mutations on treatment efficacy and ongoing trials in the context of novel therapies.

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