The Role of Trope Two in Breast Cancer

T trope is expressed in 96% or so of endometroid tumors and about two thirds of serous. In addition to HER2, now we have trope. And this is a small investigator initiated trial, 21 patients, about a third of them responded. So I think there's a signal here with an anti-trop ADC. We're going to continue to take lines of therapy. But we're going to look at new agents based on biomarkers. For today, second line treatment in the IONI-Eve patient, which is most, is Dostarlemabra Pembrotherin-S-I-Hi. If they're not, then it's P