Journey from Big Pharma to Small Biotech: Lessons in Drug Discovery

The chapter follows the speaker's transition from academia to the industry sector, detailing their experiences at Genentech and DuPont Pharmaceuticals. It explores the importance of medicinal chemists in drug discovery programs and the valuable insights gained from collaborating with biologists and pharmacologists. The narrative also touches on Insight's strategic pivot towards genetics for small molecule drug discovery and the development of a successful Janus kinase inhibitor program.