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Ep 180 Acetaminophen Poisoning – Pitfalls in Assessment and Management

Emergency Medicine Cases

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Acetaminophen Level Is Interfering With Bilirubin

Every patient who has taken an acetaminophen overdose is going to have a bump in their AST, ALT, their transaminases by the 24 hour mark. It won't be the peak, but they will start to go up. Acetaminophen concentration is interfered with by bilirubin. And so if you present with hepatotoxicity, liver enzymes that are elevated, a high bilirUBin, etc., your acetaminophen level may be positive because there's a colorometric interference with high bilirube levels.

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