The Role of Pyruvacarboxylase in the Ketogenic Diet

Glucose entering the citric acid cycle is needed for it to be burned for energy. As a result of this, pyruvacarboxylase is needed indirectly to synthesize anything fatty such as myelin sheet and lapoic acid. The biochemical adage fat burns in the flame of carbohydrate refers to the fact that fatty acids generate two carbon acetyl-CoA but cannot lead to the net synthesis of the four carbon oxaloacetate.