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PREPARE II Trial Result Presentation

Critical Care Reviews Podcast

CHAPTER

The Effects of Sedation on Hypertension

Would it be better to have a primary endpoint that was physiological based, and then just report the mortality as purely a secondary outcome? Maybe we can discuss. The intervention was unblinded by nature. It would be very hard to blind it. There's no evidence of that. So it looks like all the treatments were balanced. Other questions I'd have? This two minutes, is that really important? What about the effects after two minutes?

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