Gluten has become one of the most misunderstood aspects of modern nutrition. Let's set the record straight.

In this episode, we untangle the medical, neurological, and cultural narratives surrounding gluten, from celiac disease and non-celiac gluten sensitivity to real (and rare) cases of gluten-induced brain dysfunction.

We discuss:

• The differences between celiac disease, gluten sensitivity, and wheat allergy • How gluten affects the gut, and what 'leaky gut' really means • Whether gluten can trigger neurological symptoms like ataxia and brain fog • Why cutting out gluten without a diagnosis may do more harm than good • How wheat contributes to a healthy microbiome (and why fiber matters) • What role zonulin plays in gut permeability and immune activation • Why brain fog isn't yet well understood (and the theories behind it)

To help us decode the science (and bust the myths) of gluten, nutrition, and the brain, we're joined by two world-renowned experts:

DR. ALESSIO FASANO: pediatric gastroenterologist, research scientist, and chief of Pediatric Gastroenterology and Nutrition at Mass General for Children (MGfC), and director of the Center for Celiac Research.

DR. FRANK CUSIMANO: gastroenterologist, physician-scientist, and gut-brain health communicator with a PhD in Nutritional and Metabolic Biology from Columbia University Institute of Human Nutrition.

This is... Your Brain On Gluten.

'Your Brain On' is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai.

'Your Brain On... Gluten' • SEASON 5 • EPISODE 2

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Your Brain On... is supported by the FREE monthly Brain Box, available in our NEURO World community: http://thebraindocs.com/brainbox

Podcast Vandaag Inside met Job Knoester, dinsdag 4 november 2025

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