Alpha-Synuclein Seed Amplification in Parkinson's Progression Markers

The June 2023 replay of past episodes showcases a selection of interviews regarding the biomarker discovery in Parkinson disease. This episode begins with an overview of the latest in Parkinson’s research, including biomarker development with Dr. Bas Bloom. The episode continues with an interview with Dr. Lucilla Parnetti about the clinical application of α-synuclein seed amplification, leading into an interview with Prof. Andrew Siderowf about seed amplification in PD in the PPMI cohort. The June Neurology Recall concludes with an interview with Dr. Christopher Gibbons on skin α-synuclein in MSA and PD.

Related Podcast Links:

Biomarker and Treatment Development in Movement Disorders: https://directory.libsyn.com/episode/index/id/26775207

Alpha-synuclein Amplification for Disease Diagnosis: https://directory.libsyn.com/episode/index/id/23923047

α-Synuclein Seed Amplification in a Large Parkinson Cohort: https://directory.libsyn.com/episode/index/id/26961315

Skin α-Synuclein In MSA and PD: https://directory.libsyn.com/episode/index/id/26499948

Related Article Links: 

Research in Movement Disorders in 2022: A New Era of Biomarker and Treatment Development: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(22)00494-X/fulltex

Synuclein Seed Amplification Assays for Diagnosing Synucleinopathies: The Way Forward: https://n.neurology.org/content/99/5/195

Assessment of Heterogeneity Among Participants in the Parkinson's Progression Markers Initiative Cohort Using _-Synuclein Seed Amplification: A Cross-Sectional Study: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00109-6/fulltext

Cutaneous _-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease: https://n.neurology.org/content/100/15/e1529

Disclosures can be found at Neurology.org