S3E7: Calico’s Cynthia Kenyon on The Science of Aging
Theory and Practice
Is Cellular Senescence a Cause of Aging?
There are many things that change with age and if you fix any one of them, you can have really big beneficial effects on mouse lifespan. It's not clear to me that there is a unified theory of aging; I don't know of one. A lot of these mechanisms of aging are under the control of our genome or maybe how the genome is actually physically packed or accessed. So how can we learn about our aging from C. elegans worms? Well, it's a tiny little animal with only 1,000 cells in its somatic body but it has a relatively simple genome.
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