The Role of Resuscitation Fluids in Surviving Sepsis

We've debated the volume of fluid that was achieved between the two treatment grades but nevertheless you did achieve separation and your control arm or overall mortality was as expected so all of those were excellent so well done. Sandy we have two of them in and then Dan McCauley after that. To go one step earlier Sandy's just talked about the process promise arise trilogy if we had this conference 20 years ago we'd be sitting here talking about a study from Detroit where patients got either 5 liters or 3.5 liters in the first 6 hours with a 16% absolute risk Reduction. That's been disproven. Even a 7% absolute risk reduction is not plausible in a sepsis trial