“HATE. LET ME TELL YOU HOW MUCH I'VE COME TO HATE YOU SINCE I BEGAN AS A HAEM REG. IF THE WORD HATE WAS ENGRAVED ON EACH NANO-ANGSTROM OF THE HUNDREDS OF MILLIONS OF CONSULT NOTES I HAVE WRITTEN IT WOULD NOT EQUAL ONE BILLIONTH OF THE HATE I FEEL FOR YOU ORDERING THROMBOPHILIA TESTING INAPPROPRIATELY.” Woah - Let’s calm down, that's a bit much. Cale and Bashar are exposed to Nick’s inner monologue as the Bloody Minded Crew learn about the what, when and when not of thrombophilia testing.
TIMESTAMPS
0:52 - Nick gets stuck in an anger loop
2:19 - Intro to thrombophilia testing
4:25 - Inherited thrombophilias
5:38 - Surprise historical diversion on antithrombin
8:14 - Proteins C and S
9:31 - Factor V Leiden
10:56 - Prothrombin gene mutation
11:52 - Risk profiles in inherited thrombophilia
18:49 - Acquired thrombophilias
18:56 - Antiphospholipid syndrome
19:46 - PNH
20:22 - JAK2
21:08 - Mid-ep summary
22:28 - The world's biggest soapbox: what not to do
23:25 - Soapbox: no MTHFR pls
25:19 - Soapbox: bad times to test
26:46 - Soapbox: don't test the obvious provoked clots
27:30 - Bonus soapbox: factor V levels vs Leiden
28:54 - When SHOULD we test?
30:41 - Benefits of testing
32:33 - Clinical scenario: spoiler, no real answer
33:26 - Scenarios where you might test
37:49 - Take home messages
Support the show
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
