
TWiV 881: 50 ways to zap your virus
This Week in Virology
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Remdesiver
Remdesiver has a phosphate buried ini a lot of dihydroxy chicken wire dixon on the left part of the molecule. And then that cantem, it looks like a phosphate, so then it can be dye in tri phosphorlated o a. So theorally av moleculesthere. A one of them just has the nitrogen with nothing else, so that would have to be mono phosphorelated. The other is a pro drug where it has, has got some extra chemical groups on the inhibitor, and that those have to be taken off before e compound can be phosphorelated - but they're all nucleusite analogues. All three compounds end up being a nucleus
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