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Can We Cure Aging?: Unpacking the Interventions | Andrew Steele, PhD

The Proof with Simon Hill

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The Effects of Gene Mutations on Cholesterol Levels

The idea is that we can go in and inhibit PCSK9 and massively reduce the levels of cholesterol in the blood. The next sort of generation of this therapy has just been approved, there's something called RNA interference technology,. And these silencing RNAs, they basically degrade the RNA intermediate. And so the protein never gets made. This is much, much better than a drug or an antibody, because it seems to last, I think, six, three, six, nine months.

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