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Katalin Karikó — Forging the mRNA Revolution

The Joe Walker Podcast

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The Role of Proteins in Immune Response to Coronavirus

Carti: Post translational modifications are really important in regulating a proteins function. Certain amino acids can have a phosphate group added to them that can have a big effect on protein. Sugars can also be added and affect the proteins function. And when you inject the cell, knows what to do because certain amino acid presence will say how much sugar is there. Carti: With the RNA, you don't need to purify - but you can also generate intracellular proteins which will be worked inside the cell.

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