Alc Inhibitor Response Rates Compared to Cresontinib

lower latinib has shown high response rates particularly if you're still out dependent with an alc resistance mutation so here this study led by dr solomon was published in the newling journal and then more recently in lancet respiratory medicine. We can see a significant improvement progression free survival with a hazard ratio of 0.27 but what's really striking in my mind is that with three years of follow-up unblinded independent review we still haven't hit the median. Lower latinib does have a unique toxicity profile compared to some of the second generation inhibitors but i think the bigger thing that many of us um you know have seen with this agent are these neurocognitive or