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Journal Club: Remodeling Oncogenic Transcriptomes with Ben Cravatt and Gene Yeo

Raising Health

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The Effect of RNA Binding Proteins on Cell Growth

In this case, we knew we want to do like you said, we wanted to suppress the androgen receptors. Let's look at that. Let's not look at three days later how that might affect cell growth. There were a number of subtle ways in which you enriched your ability to ask questions specifically about RNA binding proteins. You looked for transcript changes quite soon after exposing the cells to the compound library within six hours. It was much easier to tease out in four hours after treatment by looking at the androgen receptor.

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