Unraveling Clonal Hematopoiesis and Stem Cell Dynamics

This chapter explores clonal hematopoiesis of indeterminate potential (CHIP) and its links to aging and diseases like cardiovascular issues. It highlights pivotal scientific discoveries and advancements in flow cytometry that enhanced the understanding of hematopoietic stem cell behaviors and interactions within their niches. The narrative emphasizes the complexity of stem cell differentiation and the evolving perspectives on microenvironments that influence stem cell functionality and health outcomes.