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Mendelian Randomization: How the Natural Assortment of Genes Can Mimic Randomized Clinical Trials

JAMA Clinical Reviews

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Causal Inference and Mendelian Randomization in Biomedical Research

The chapter explores the challenges of drawing causal relationships in observational epidemiologic studies, emphasizing how human genetics through Mendelian randomization can provide insights before conducting randomized trials, offering a unique approach for causal inference in biomedical research.

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