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Oncology Today with Dr Neil Love: Key Presentations in Acute Myeloid Leukemia and Myelodysplastic Syndromes from the 2022 ASH Annual Meeting

Hematologic Oncology Update

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A's of Venn in KMT2A Rearranged Leukemia

There's another drug, a class of drugs called thick inhibitors that seem to work in NPM1 and KMT2A rearranged leukemia being tested. Different mechanism of action but same idea turned down that Hox-Mease cluster with these drugs. It works well but not as well as 7 plus 3 in younger patients? Well, we don't know that. I mean, nobody's given to my knowledge A's event to younger patients with NPM1 mutations.

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